A discussion, centering on the term subcompact publishing, is emerging about using simpler publishing and reading tools for the web and mobile devices.
More specifically, it’s about shrugging off the previous modes of thought that came with the publishing business and approaching the whole concept in a new way.
Good stuff to think about, but the one that everyone should implement right away? Get rid of pagination, like Mod says, move to scroll only. The popularization of page turning on screens is one of the most backwards-facing things Apple did with the iPad.